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How the Street's calls on biotech played out

Sell-side price targets on biotech names over the last two years, checked over each firm's own horizon: 131 of 363 resolved targets (36%) were reached while they stood, 219 were replaced by the same firm first, and 13 fell short at their deadline.

5 names · 16 firms with 8+ resolved targets here · checked through 2026-10-29. Rebuilt every morning.

Targets reached while they stood
36.1% of 363
Replaced before the deadline
60.3%
Buy / Hold / Sell
54 / 42 / 4%

Firm by firm on biotech

#FirmTargets reachedReplaced earlyShortResolvedRatings vs sectorNames
1 RBC Capital 10 (26%) 29039 1 of 1 AMGN GILD MRNA REGN VRTX
2 Morgan Stanley 7 (18%) 31038 1 of 1 AMGN GILD MRNA REGN VRTX
UBS 9 (36%) 16025 0 of 2 AMGN GILD MRNA REGN VRTX
Truist Securities 8 (35%) 15023 0 of 3 AMGN GILD REGN VRTX
Citigroup 8 (36%) 14022 2 of 3 AMGN GILD MRNA REGN VRTX
Piper Sandler 5 (25%) 12320 2 of 5 AMGN GILD MRNA REGN VRTX
Wells Fargo 9 (50%) 9018 1 of 2 AMGN GILD REGN VRTX
Cantor Fitzgerald 14 (82%) 3017 0 of 2 AMGN GILD REGN VRTX
BMO Capital 5 (29%) 11117 3 of 4 AMGN GILD REGN VRTX
JPMorgan 6 (35%) 11017 3 of 4 GILD MRNA REGN VRTX
Barclays 4 (27%) 10115 0 of 1 AMGN GILD MRNA REGN VRTX
Bank of America 4 (29%) 10014 1 of 4 AMGN GILD MRNA REGN VRTX
Canaccord Genuity 6 (50%) 6012 1 of 1 AMGN REGN VRTX
Oppenheimer 2 (18%) 8111 1 of 2 AMGN GILD REGN VRTX
Guggenheim 2 (22%) 619 1 of 2 AMGN REGN VRTX
Goldman Sachs 3 (38%) 418 1 of 1 AMGN GILD MRNA REGN

Numbered firms have 30+ resolved targets in this sector and are ordered by the share reached; the rest are listed by volume, unranked. A record inside one sector is a slice of a slice: none of these counts is a measure of skill, and none carries a letter. How targets and ratings are checked →

The names

AMGNGILDMRNAREGNVRTX Biotech vs XBI →

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How calls are checked

Every call is checked on the firm's own terms. A price target is followed until its own deadline (12 months unless the firm publishes a different horizon) and ends as reached (the stock closed at or beyond it while it stood), replaced (the same firm set a new target first) or short at deadline. A rating is compared with the stock's sector SPDR ETF on total return over the rating's life, because most big-firm ratings are relative: Overweight means "beat its peers", not "go up". Hold-type ratings are tracked, not graded. A firm is numbered only with 30+ resolved targets, and a letter prints only for a firm's whole record where an exact test separates it from a coin flip. None of this is a verdict on anyone's skill, and one day is never a grade. The full method →

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