VRTX analyst scorecard · Vertex Pharmaceuticals
50 rating changes on VRTX in the last 12 months. 50% of bullish calls were right at 30 days. Street grade C on 41 scored calls. Consensus target $569, 10% above the last close.
Graded through 2026-09-14 · last close $519.55 (2026-09-14). Rebuilt every morning.
Street grade
C 51.2%
Rating changes, 12 mo
50
Bullish calls right at 30d
50.0% of 40
Bearish calls right at 30d
—
Consensus target
$569 +9.6%
Firms covering
27
Price targets hit (90d)
20.0% of 40
Holds on VRTX, read: 0 cut to or raised to Hold (graded as the change) · 1 Holds whose target leaned 10%+ one way (graded that way) · 9 true Holds, not graded.
The 8 upgrades on VRTX came after an average +2.9% move in the prior 30 days, and the stock averaged -1.6% in the 90 days after.
Firm by firm
| Firm | Calls | Scored | Right | Accuracy | Grade | Avg 30d | Avg 90d | Latest | Date | Target |
|---|---|---|---|---|---|---|---|---|---|---|
| Barclays | 5 | 4 | 3 | 75.0% | A | +5.1% | +1.3% | Overweight | 2026-08-05 | $617 |
| RBC Capital | 5 | 4 | 2 | 50.0% | C | +0.6% | +2.0% | Outperform | 2026-07-07 | $570 |
| Morgan Stanley | 6 | 5 | 1 | 20.0% | F | -1.2% | +5.4% | Overweight | 2026-05-05 | $616 |
| UBS | 3 | 3 | 3 | — | — | +6.2% | +0.7% | Buy | 2026-07-13 | $585 |
| Bernstein | 2 | 2 | 2 | — | — | +2.1% | +3.2% | Outperform | 2026-05-05 | $572 |
| Leerink Partners | 2 | 2 | 2 | — | — | +7.0% | +8.8% | Outperform | 2025-12-29 | $525 |
| TD Cowen | 1 | 1 | 1 | — | — | +16.6% | — | Buy | 2026-08-04 | $550 |
| Cantor Fitzgerald | 1 | 1 | 1 | — | — | +16.6% | — | Overweight | 2026-08-04 | $595 |
| Baird | 1 | 1 | 1 | — | — | -7.3% | — | Underperform | 2026-07-07 | $350 |
| Evercore ISI Group | 1 | 1 | 1 | — | — | +2.7% | -7.1% | Outperform | 2026-01-23 | $530 |
| Wells Fargo | 1 | 1 | 1 | — | — | +4.3% | +12.3% | Overweight | 2025-12-10 | $515 |
| Truist Securities | 3 | 3 | 2 | — | — | +3.6% | -9.5% | Buy | 2026-08-05 | $565 |
| Citigroup | 2 | 2 | 1 | — | — | -3.1% | -0.2% | Buy | 2026-03-10 | $585 |
| Canaccord Genuity | 4 | 0 | 0 | — | — | +4.8% | +5.2% | Hold | 2026-08-04 | $442 |
| HC Wainwright & Co. | 3 | 3 | 0 | — | — | -6.6% | -9.4% | Buy | 2026-03-10 | $641 |
| Oppenheimer | 2 | 2 | 0 | — | — | -7.8% | -9.8% | Outperform | 2026-03-10 | $600 |
| Stifel | 2 | 0 | 0 | — | — | +1.6% | +1.8% | Hold | 2026-02-13 | $466 |
| Maxim Group | 1 | 1 | 0 | — | — | -2.3% | +0.3% | Buy | 2026-03-18 | $575 |
| Bank of America | 1 | 1 | 0 | — | — | -10.5% | -11.3% | Buy | 2026-03-10 | $598 |
| Jefferies | 1 | 1 | 0 | — | — | -10.5% | -11.3% | Buy | 2026-03-10 | $580 |
| Scotiabank | 1 | 1 | 0 | — | — | -5.2% | -8.3% | Sector Perform | 2026-02-13 | $558 |
| Wolfe Research | 1 | 1 | 0 | — | — | -2.0% | -7.3% | Outperform | 2026-01-06 | $548 |
| JPMorgan | 1 | 1 | 0 | — | — | -2.8% | +11.2% | Overweight | 2025-10-08 | $530 |
Dimmed rows have fewer than 4 scored calls on VRTX — too few to grade.
Every call, last 12 months
| Date | Firm | Change | Action | Graded as | Price at call | Run before | +30d | +60d | +90d | Target · 90d check | Hit |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-08-05 | Truist Securities | Buy → Buy | maintained | Bullish | $484.83 | -8.4% | +12.6% | — | — | $565 | ✓ |
| 2026-08-05 | Barclays | Overweight → Overweight | maintained | Bullish | $484.83 | -8.4% | +12.6% | — | — | $617 | ✓ |
| 2026-08-04 | TD Cowen | Buy → Buy | maintained | Bullish | $478.71 | -9.3% | +16.6% | — | — | $550 | ✓ |
| 2026-08-04 | Cantor Fitzgerald | Overweight → Overweight | maintained | Bullish | $478.71 | -9.3% | +16.6% | — | — | $595 | ✓ |
| 2026-08-04 | Canaccord Genuity | Hold → Hold | maintained | True hold · target -7% | $478.71 | -9.3% | +16.6% | — | — | $442 | not graded |
| 2026-07-13 | UBS | Buy → Buy | maintained | Bullish | $480.25 | +7.9% | +9.5% | +7.3% | — | $585 | ✓ |
| 2026-07-13 | Truist Securities | Buy → Buy | maintained | Bullish | $480.25 | +7.9% | +9.5% | +7.3% | — | $560 | ✓ |
| 2026-07-07 | RBC Capital | Outperform → Outperform | maintained | Bullish | $522.25 | +16.9% | -7.3% | +1.3% | — | $570 | ✗ |
| 2026-07-07 | Baird | Underperform → Underperform | maintained | Bearish | $522.25 | +16.9% | -7.3% | +1.3% | — | $350 | ✓ |
| 2026-05-06 | Barclays | Overweight → Overweight | maintained | Bullish | $427.65 | -1.5% | +4.5% | +23.8% | +11.9% | $615 missed | ✓ |
| 2026-05-05 | Canaccord Genuity | Hold → Hold | maintained | True hold · target +2% | $424.36 | -3.3% | +4.1% | +24.8% | +10.9% | $436 hit | not graded |
| 2026-05-05 | Morgan Stanley | Overweight → Overweight | maintained | Bullish | $424.36 | -3.3% | +4.1% | +24.8% | +10.9% | $616 missed | ✓ |
| 2026-05-05 | Bernstein | Outperform → Outperform | maintained | Bullish | $424.36 | -3.3% | +4.1% | +24.8% | +10.9% | $572 missed | ✓ |
| 2026-05-05 | RBC Capital | Outperform → Outperform | maintained | Bullish | $424.36 | -3.3% | +4.1% | +24.8% | +10.9% | $543 missed | ✓ |
| 2026-04-30 | Canaccord Genuity | Hold → Hold | maintained | True hold · target +2% | $427.38 | -4.3% | +2.6% | +16.9% | +13.1% | $437 hit | not graded |
| 2026-04-10 | Morgan Stanley | Overweight → Overweight | maintained | Bullish | $436.27 | -11.4% | -0.2% | +2.2% | +13.8% | $612 missed | ✗ |
| 2026-03-18 | Maxim Group | Hold → Buy | upgrade | Bullish | $451.59 | -8.1% | -2.3% | -3.3% | +0.3% | $575 missed | ✗ |
| 2026-03-11 | Truist Securities | Buy → Buy | maintained | Bullish | $492.38 | +4.6% | -11.4% | -11.6% | -9.5% | $525 missed | ✗ |
| 2026-03-10 | Morgan Stanley | Overweight → Overweight | maintained | Bullish | $499.17 | +4.5% | -10.5% | -12.8% | -11.3% | $596 missed | ✗ |
| 2026-03-10 | Bank of America | Buy → Buy | maintained | Bullish | $499.17 | +4.5% | -10.5% | -12.8% | -11.3% | $598 missed | ✗ |
| 2026-03-10 | Citigroup | Buy → Buy | maintained | Bullish | $499.17 | +4.5% | -10.5% | -12.8% | -11.3% | $585 missed | ✗ |
| 2026-03-10 | Oppenheimer | Outperform → Outperform | maintained | Bullish | $499.17 | +4.5% | -10.5% | -12.8% | -11.3% | $600 missed | ✗ |
| 2026-03-10 | Jefferies | Buy | initiated | Bullish | $499.17 | +4.5% | -10.5% | -12.8% | -11.3% | $580 missed | ✗ |
| 2026-03-10 | HC Wainwright & Co. | Buy → Buy | maintained | Bullish | $499.17 | +4.5% | -10.5% | -12.8% | -11.3% | $641 missed | ✗ |
| 2026-02-17 | Canaccord Genuity | Hold → Hold | maintained | True hold · target -7% | $477.32 | +8.2% | -4.0% | -8.0% | -8.5% | $441 hit | not graded |
| 2026-02-17 | Barclays | Overweight → Overweight | maintained | Bullish | $477.32 | +8.2% | -4.0% | -8.0% | -8.5% | $607 missed | ✗ |
| 2026-02-17 | HC Wainwright & Co. | Buy → Buy | maintained | Bullish | $477.32 | +8.2% | -4.0% | -8.0% | -8.5% | $591 missed | ✗ |
| 2026-02-13 | Scotiabank | Sector Perform → Sector Perform | maintained | Leans bullish · Sector Perform, target +13% | $491.47 | +9.3% | -5.2% | -9.6% | -8.3% | $558 missed | ✗ |
| 2026-02-13 | RBC Capital | Outperform → Outperform | maintained | Bullish | $491.47 | +9.3% | -5.2% | -9.6% | -8.3% | $541 missed | ✗ |
| 2026-02-13 | Stifel | Hold → Hold | maintained | True hold · target -5% | $491.47 | +9.3% | -5.2% | -9.6% | -8.3% | $466 hit | not graded |
| 2026-02-13 | Oppenheimer | Perform → Outperform | upgrade | Bullish | $491.47 | +9.3% | -5.2% | -9.6% | -8.3% | $540 missed | ✗ |
| 2026-02-13 | HC Wainwright & Co. | Buy → Buy | maintained | Bullish | $491.47 | +9.3% | -5.2% | -9.6% | -8.3% | $518 missed | ✗ |
| 2026-01-28 | Barclays | Equal-Weight → Overweight | upgrade | Bullish | $477.91 | +3.9% | +4.0% | -7.3% | -10.0% | $606 missed | ✓ |
| 2026-01-26 | UBS | Buy → Buy | maintained | Bullish | $476.84 | +3.0% | +1.3% | -9.2% | -10.7% | $545 missed | ✓ |
| 2026-01-23 | Evercore ISI Group | Outperform → Outperform | maintained | Bullish | $468.41 | +1.2% | +2.7% | -4.2% | -7.1% | $530 missed | ✓ |
| 2026-01-22 | RBC Capital | Sector Perform → Outperform | upgrade | Bullish | $467.35 | +1.8% | +2.9% | -3.5% | -6.3% | $546 missed | ✓ |
| 2026-01-12 | Bernstein | Market Perform → Outperform | upgrade | Bullish | $460.59 | +1.9% | +0.1% | +1.9% | -4.5% | — | ✓ |
| 2026-01-06 | Wolfe Research | Peer Perform → Outperform | upgrade | Bullish | $468.38 | +2.8% | -2.0% | -1.6% | -7.3% | $548 missed | ✗ |
| 2025-12-29 | Leerink Partners | Outperform → Outperform | maintained | Bullish | $459.78 | +6.0% | +3.9% | +8.1% | -3.6% | $525 missed | ✓ |
| 2025-12-10 | Wells Fargo | Overweight → Overweight | maintained | Bullish | $444.64 | +5.6% | +4.3% | +5.9% | +12.3% | $515 hit | ✓ |
| 2025-12-05 | Morgan Stanley | Overweight → Overweight | maintained | Bullish | $455.48 | +9.2% | -1.5% | +2.2% | +1.2% | $564 missed | ✗ |
| 2025-12-03 | Morgan Stanley | Equal-Weight → Overweight | upgrade | Bullish | $463.13 | +8.7% | -2.4% | +1.9% | +2.4% | $516 missed | ✗ |
| 2025-11-07 | UBS | Buy → Buy | maintained | Bullish | $409.47 | -2.8% | +8.0% | +14.4% | +12.1% | $546 missed | ✓ |
| 2025-11-04 | RBC Capital | Sector Perform → Sector Perform | maintained | True hold · target -1% | $421.67 | +4.5% | +8.5% | +6.4% | +11.9% | $415 missed | not graded |
| 2025-11-04 | Barclays | Equal-Weight → Equal-Weight | maintained | True hold · target -1% | $421.67 | +4.5% | +8.5% | +6.4% | +11.9% | $414 missed | not graded |
| 2025-11-04 | Stifel | Hold → Hold | maintained | True hold · target +5% | $421.67 | +4.5% | +8.5% | +6.4% | +11.9% | $445 hit | not graded |
| 2025-10-10 | Morgan Stanley | Equal-Weight → Equal-Weight | maintained | True hold · target +7% | $407.79 | — | +3.3% | +7.2% | +15.2% | $438 hit | not graded |
| 2025-10-08 | JPMorgan | Overweight → Overweight | maintained | Bullish | $421.15 | — | -2.8% | +5.0% | +11.2% | $530 missed | ✗ |
| 2025-10-02 | Citigroup | Buy → Buy | maintained | Bullish | $408.85 | — | +4.2% | +4.1% | +10.9% | $575 missed | ✓ |
| 2025-09-25 | Leerink Partners | Market Perform → Outperform | upgrade | Bullish | $381.87 | — | +10.0% | +11.0% | +21.2% | $456 hit | ✓ |
Also in Biotech
Interactive version with the price chart and target overlay: Scorecard tab on the dashboard. All covered names: index.
How the grading works
Every sell-side rating change from the last 365 days is priced the day it lands and checked again 30, 60 and 90 days later. A call is a hit when the stock moved in the called direction at 30 days. Buy- and Sell-side ratings call their own direction. A Hold is read, not waved through: a downgrade to Hold is graded as a bearish call and an upgrade to Hold as a bullish one, and a maintained Hold whose price target sits 10%+ above the price leans bullish (10%+ below, leans bearish) and is graded that way. A Hold with a target close to the price is a true Hold and is not graded at all. Every call with a price target also gets a target check 90 days later: hit (reached it or within 5%), close (covered at least half the distance) or missed. A firm's accuracy on a single name prints only after 4 scored calls, and a firm gets its own page only after 10 scored calls across every covered name — below that a percentage is noise. "Run before the call" is the stock's move over the 30 calendar days before the rating landed. Data: Yahoo Finance rating history and daily closes, rebuilt each morning. Nothing on this page is advice.
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