Biotech vs XBI
1 of 5 biotech headliners beat XBI over the last year (1 of 5 over six months, 0 of 5 over three). Every line is measured against the benchmark itself, so the zero line is XBI.
Weekly closes through 2026-09-14. The zero line is the benchmark: a name "beats" when its total return over the window is higher than XBI's. Rebuilt every morning.
Total return
| Name | 6M | vs bench | 1Y | vs bench | 3Y | vs bench | Since |
|---|---|---|---|---|---|---|---|
| XBI benchmark | +31.1% | 0 | +65.0% | 0 | +116.2% | 0 | — |
| AMGN | +9.1% | -22.0 | +33.0% | -32.0 | +41.8% | -74.4 | 2021-09 |
| GILD | +6.1% | -25.0 | +27.6% | -37.4 | +94.1% | -22.1 | 2021-09 |
| VRTX | +14.4% | -16.7 | +35.6% | -29.4 | +48.6% | -67.6 | 2021-09 |
| REGN | +8.4% | -22.7 | +34.2% | -30.8 | -3.7% | -119.9 | 2021-09 |
| MRNA | +184.3% | +153.2 | +478.8% | +413.8 | +46.1% | -70.1 | 2021-09 |
A name whose history starts inside a window is measured from its first bar, not the window start — the "Since" column says where.
Headliners
Benchmarks available on the dashboard: XBI, IBB.
The wider biotech universe
The dashboard's Sleepers view screens these 31 lesser-covered names for the ones beating XBI on a trailing basis, with liquidity, price and coverage floors so nothing untradeable or already crowded gets through.
Other baskets
Interactive chart with 6M–5Y windows, relative / indexed / drawdown modes and the sleeper screen: Baskets tab.
How the grading works
Every sell-side rating change from the last 365 days is priced the day it lands and checked again 30, 60 and 90 days later. A call is a hit when the stock moved in the called direction at 30 days. Buy- and Sell-side ratings call their own direction. A Hold is read, not waved through: a downgrade to Hold is graded as a bearish call and an upgrade to Hold as a bullish one, and a maintained Hold whose price target sits 10%+ above the price leans bullish (10%+ below, leans bearish) and is graded that way. A Hold with a target close to the price is a true Hold and is not graded at all. Every call with a price target also gets a target check 90 days later: hit (reached it or within 5%), close (covered at least half the distance) or missed. A firm's accuracy on a single name prints only after 4 scored calls, and a firm gets its own page only after 10 scored calls across every covered name — below that a percentage is noise. "Run before the call" is the stock's move over the 30 calendar days before the rating landed. Data: Yahoo Finance rating history and daily closes, rebuilt each morning. Nothing on this page is advice.
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